Research Papers

Scientific Papers

2012

Stough, C., Downey, L., Silber, B., Lloyd, J., Kure, C., Wesnes, K. and Camfield, D.  The effects of 90-day supplementation with the Omega-3 essential fatty acid docosahexanoic acid (DHA) on cognitive function and visual acuity in a healthy aging population. Neurobiology of Aging.  2012: 33: 824.e1-824.e3.

Skilton, M.R., Ayer, J.G., Harmer, J.A., Webb, K., Leeder, S.R., Marks, G.B. and Celermajer, D.S.  Impaired fetal growth and arterial wall thickening: A randomized trial of omega-3 supplementation. Pediatrics.  2012: 129:e698-e703.

Keenan, M.J., Martin, R.J., Raggio, A.M., McCutcheon, K.L., Brown, I.L., Birkett, A., Newman, S.S., Skaf, J., Hegsted, M., Tulley, R.T., Blair, E. and Zhou, J.  High-amylose resistant starch increases hormones and improves structure and function of the gastrointestinal tract: a microarray study. Journal of Nutrigenetics and Nutrigenomics.  2012: 5: 26-44.

2011

Patch, C.S.  Omega-3 fatty acids affecting cardiovascular disease. Nutrition Management in general Practice.  2011: 2: 10-11.

Manly, B.J., Makrides, M., Collins, C.T., McPhee, A.J., Gibson, R.A., Ryan, P., Sullivan, P.G. and Davis, P.G.  High-dose docosahexanoic acid supplementation of preterm infants: respiratory and allergy outcomes. Pediatrics. 2011: 128(1): E71-E77.

Kumar,S., Sutherland, F., Wheeler, M., Heck, P.M., Lee, G., Teh, A.W., Garg, M., Morgan, J.G. and Sparks, P.B. Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial mechanical function after reversion of atrial arrhythmias to sinus rhythm: Reversal of tachycardia-mediated atrial cardiomyopathy with fish oils. Heart Rhythm. 2011: 8:643-649.

Kumar,S., Sutherland, F., Rosso, R., Teh, A.W., Lee, G., Heck, P.M., Feldman, A., Medi, C., Watt, S., Garg, M. and Sparks, P.B. Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial electrophysiology. Heart Rhythm. 2011: 8:562-568.

Collins, C., Makrides, M., Gibson, R., McPhee, A., Davis, P., Doyle, L., Simmer, K., Colditz, P., Morris, S., Sullivan, T and Ryan, P. Pre- and post-term growth in pre-term infants supplemented with higher-dose DHA: a randomised controlled trial. British Journal of Nutrition. 2011; Marc 29:1-9 [Epub ahead of print]

2010

Peoples, G.E. and McLennan, P.L. Dietary fish oil reduces skeletal muscle oxygen consumption, provides fatigue resistance and improves contractile recovery in the rat in vivo hindlimb. Brit J Nutr 2010; 104.

Slee, E.L., McLennan, P.L., Owen, A.J. and Theiss, M.L. Low dietary fish oil threshold for myocardial membrane n-3 PUFA enrichment independent of n-6 PUFA intake in rats. J Lipid Res 2010; 51: 1841-1848.

Smithers LG, Collins CT, Simmonds LA, Gibson RA, McPhee A and Makrides M. 2010. Feeding preterm infants milk with a higher dose of docosahexaenoic acid than that used in current practice does not influence language or behavior in early childhood: a follow-up study of a randomized controlled trial. Am J Clin Nutr. 91:628-634.

Presentations at scientific meetings:

McEwen, B. Effects of low dose omega-3 PUFA on platelet function and coagulation. Abstract presentation at the International Society for Laboratory Hematology 2010, the XXIIIrd International Symposium on Technological Innovations in Laboratory Hematology, May 2010.

McLennan, P.L., Abdukeyum G.G., Owen A.J. and Larkin T.A. Fish oil induced increase in membrane peroxidation potential paradoxically promotes preconditioning. J Heart Disease, 2010; 7: 85. Abstract presentation at International Academy of Cardiology,
15th World Congress on heart Disease, Vancouver Canada, July 24-27 2010.

McLennan, P.L. Experimental evidence for the use of fish and fish oil in cardiology: biological plausibility of nutritional preconditioning by omega-3 fatty acids. Presentation at Cardiovascular Health Research Unit, Dept Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, USA, July 2010.

Meldrum, S.J., Simmer, K., D’Vaz, N., Hird, K. and Prescott, S.L. Effect of high-dose
fish oil supplementation during early infancy on term infant neurodevelopment and behavior. Poster presentation ISSFAL June 2010.

2009

Brown MA, Storlien LH, Huang XF, Tapsell LC, Elise PL, Higgins JA and Brown IL (2009). Dietary fat and carbohydrate composition: metabolic disease. Chapter 21.
In: Fat Detection: Taste, Texture, and Post Ingestive Effects. Edited by J-P Montmayeur & J le Coutre. CRC Press (Boca Raton, USA): 533-560.

Clayton, E.H., Hanstock, T.L., Hirneth, S.J., Garg, M.L. and Hazell, P.L. Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation. European Journal of Clinical Nutrition 2009; 63: 1037-1040. Short Communication

Huggins, C.E., Curl, C.L., Patel, R., McLennan, P.L., Theiss, M.L., Pedrazzini, T., Pepe, S. and Delbridge, L.M. Dietary fish oil is anti-hypertrophic but does not enhance post-ischemic myocardial function in female mice. Am J Physiol Heart Circ Physiol 2009; 296: H957–H966.

Makrides, M., Gibson, R.A., McPhee, A.J., Collins, C.T., Davis, P.G., Doyle, L.W., Simmer, K., Colditz, P.B., Morris, S., Smithers, L.G., Wilson, K. And Ryan, P. 2009. “Neurodevelopmental outcomes of preterm infants fed high-dose docosahexaenoic acid. Journal of the American Medical Association. 301 (2): 175-182.

Micallef, M. and Garg, M. Anti-inflammatory and cardioprotective effects of n-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals. Atherosclerosis 2009; 204(2):476-82.

Presentations at scientific meetings:

Morel-Kopp, M., McEwen, B., Qiang Chen, Q. and Ward, C.M. Long term effect of tomato juice and fish oil on platelet function and thrombus formation. Poster
presentation XXII Congress International Society on Thrombosis and Haemostasis, Boston July 11- 16, 2009.

2008

Abdukeyum, G.G., A.J. Owen, and P.L. McLennan. 2008. "Dietary (n-3) Long-Chain Polyunsaturated Fatty Acids Inhibit Ischemia and Reperfusion Arrhythmias and Infarction in Rat Heart Not Enhanced by Ischemic Preconditioning." The Journal of Nutrition 138 (10): 1902-1909.

Brown I and Patch C (2008). Long chain omega-3 PUFAs and their role in healthy ageing. Chemistry in Australia. 75(10): 14-16.

Buckley, J.D., S. Burgess, K.J. Murphy, and P.R.C. Howe. 2008. "DHA-rich fish oil lowers heart rate during submaximal exercise in elite Australian Rules footballers." Journal of Science and Medicine in Sport. doi:10.1016/j.jsams.2008.01.011

Clayton, E.H., Hanstock, T.L., Hirneth, S.J., Kable, C.J., Garg, M.L. and Hazell, P.L. Long-chain omega-3 polyunsaturated fatty acids in the blood of children and adolescents with juvenile bipolar disorder. Lipids 2008;43:1031-1038.

Larter, C.Z., Yeh, M.M., Cheng, J., Williams, J., Brown, S., dela Pena, A., Bell-Anderson, K.S. and Farrell, G.C. Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation. J Gastroenterol Hepatol 2008;23(2):267-75.

Milte, C.M., Coates, A.M., Buckley, J.D., Hill, A.M. and Howe, P.R.C. Dose-dependent effects of docosahexaenoic acid-rich fish oil on erythrocyte docosahexaenoic acid and blood lipid levels. British Journal of Nutrition 2008:99:1083-1088.

Ninio D.M., Hill A.M., Howe P.R., Buckley J.D. and Saint DA. 2008. “Docosahexaenoic acid-rich fish oil improves heart rate variability and heart rate responses to exercise in overweight adults.” British Journal of Nutrition. 100(5):1097-103.

Rees, A., Austin, M.P. and Parker, G.B. Omega-3 fatty acids as a treatment for perinatal depression: randomized double-blind placebo-controlled trial. Australian and New Zealand Journal of Psychiatry 2008; 42:199-205.

Smithers, L.G., R.A. Gibson, A. McPhee, and M. Makrides. 2008. "Higher dose of docosahexaenoic acid in the neonatal period improves visual acuity of preterm infants: results of a randomized controlled trial." America Journal of Clinical Nutrition 88 (4): 1049-1056.

Smithers L.G., Gibson R.A., McPhee A and Makrides M. 2008. “Effect of two doses of docosahexaenoic acid (DHA) in the diet of preterm infants on infant fatty acid status: results from the DINO trial.” Prostaglandins Leukotrienes & Essential Fatty Acids. 79(3-5):141-6.

2007

Grenyer, B.F.S., T. Crowe, B. Meyer, A.J. Owen, E.M. Grigonis-Deane, P. Caputi, and P.R.C. Howe. 2007. "Fish oil supplementation in the treatment of major depression: a randomised double-blind placebo-controlled trial." Progress in Neuro-Psychopharacology & Biological Psychiatry 31: 1393-1396.

Hill, A.M., Buckley, J.D., Murphy, K.J. and Howe, P.R.C. Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. Am J Clin Nutr 2007;85:1267–74.

Hill, A.M., Worthley, C., Murphy, K.J., Buckley, J.D., Ferrante, A. and Howe, P.R.C. n-3 Fatty acid supplementation and regular moderate exercise: differential effects of a combined intervention on neutrophil function. British Journal of Nutrition 2007; 98: 300–309.

Meyer, B.J., T. Hammervold, A.C. Rustan, and P.R.C. Howe. 2007. "Dose-dependent effects of docosahexaenoic acid supplementation on blood lipids in statin-treated hyperlipidaemic subjects." Lipids 42: 109-115.

Nguyen, C.T.O., Bui, B.V., Sinclair, A.J. and Vingrys, A.J. Dietary omega 3 fatty acids decrease intraocular pressure with age by increasing aqueous outflow. Invest Ophthalmol Vis Sci. 2007;48: 756–762.

Pepe, S., and P.L. McLennan. 2007. "(n-3) long chain PUFA dose-dependently increase oxygen utilisation efficiency and inhibit arrhythmias after saturated fat feeding in rats." The Journal of Nutrition 133: 2377-2383.